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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXN All Species: 22.73
Human Site: S230 Identified Species: 41.67
UniProt: P49023 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P49023 NP_001074324.1 591 64533 S230 E L E S S V P S P V P A I T V
Chimpanzee Pan troglodytes XP_001159942 589 64154 S228 E L E S S V P S P V P A I T V
Rhesus Macaque Macaca mulatta XP_001085795 563 61555 S236 E L E S S V P S P V P A I T V
Dog Lupus familis XP_543425 664 72715 S241 E L E S S V P S P V P A I T V
Cat Felis silvestris
Mouse Mus musculus Q8VI36 591 64458 S230 E L E S S V P S P V P A I T V
Rat Rattus norvegicus Q66H76 586 64001 G221 E S N N L L G G K A G P L M K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P49024 559 61224 S231 E L E S S V P S P V P A I T V
Frog Xenopus laevis Q2TCH4 506 55983 P191 P R S T A C V P K D L E D A P
Zebra Danio Brachydanio rerio Q6P7E4 419 45574 K104 T S S S S Q P K Y S F A P S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523601 581 64668 G218 T G P D G P V G T V E E Q I V
Honey Bee Apis mellifera XP_624308 559 62451 E215 D L M A S L S E F K P V C K L
Nematode Worm Caenorhab. elegans Q09476 413 46434 V98 E S R L N P P V Y S R P S V Q
Sea Urchin Strong. purpuratus XP_780574 695 76058 Q313 P S Q Q Q H Q Q P M S R V M T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 92.5 83.1 N.A. 93.7 74.9 N.A. N.A. 84.7 41.2 21.6 N.A. 43.1 43.3 33.8 43.4
Protein Similarity: 100 99.1 92.8 85.2 N.A. 95.7 78.3 N.A. N.A. 88.4 54.3 36.5 N.A. 54.8 57 47 56.2
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. N.A. 100 0 26.6 N.A. 13.3 20 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. N.A. 100 13.3 33.3 N.A. 13.3 46.6 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 0 0 0 8 0 54 0 8 0 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % C
% Asp: 8 0 0 8 0 0 0 0 0 8 0 0 8 0 0 % D
% Glu: 62 0 47 0 0 0 0 8 0 0 8 16 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % F
% Gly: 0 8 0 0 8 0 8 16 0 0 8 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 47 8 0 % I
% Lys: 0 0 0 0 0 0 0 8 16 8 0 0 0 8 8 % K
% Leu: 0 54 0 8 8 16 0 0 0 0 8 0 8 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 8 0 0 0 16 0 % M
% Asn: 0 0 8 8 8 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 16 0 8 0 0 16 62 8 54 0 54 16 8 0 8 % P
% Gln: 0 0 8 8 8 8 8 8 0 0 0 0 8 0 8 % Q
% Arg: 0 8 8 0 0 0 0 0 0 0 8 8 0 0 0 % R
% Ser: 0 31 16 54 62 0 8 47 0 16 8 0 8 8 0 % S
% Thr: 16 0 0 8 0 0 0 0 8 0 0 0 0 47 16 % T
% Val: 0 0 0 0 0 47 16 8 0 54 0 8 8 8 54 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 16 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _